Asthma

Asthma

Inflammed, Narrow, Swollen Airways

Causes and Triggers

Genetic, Environment (Pets, Dust, cold, dry air, & smoke), exercise-induced, cold windy weather, cockroaches, Aspirin, NSAIDs such as ibuprofein, ACE inhibitors, Non-selective beta blockers such as propanolol & GERD.

Signs and Symptoms

Dyspnea, Wheezing, tachypnea, chest tightness, coughing, anxiety, mucus, air trapping (retaining CO2).

Long-Action

Long-Acting Beta 2 Agonist. E.g., Salmeterol

Short-Action

Beta2 agonist used for rescue. E.g., Albuterol

Corticosteroids

Prednisone (oral) & Beclomethasone, Fluticasone, Budesonide (inhaled)

Anticholinergics

Ipratropium Bromide

Leukotriene Modifiers

Montelukast

Omalizumab

Blocks immunoglobulin IgE. Given subQ in poorly controlled asthma

Mast cell stabilizers

Cromolyn. Side effects: temporary burning sensation, teary eyes, sneezing, bad taste mouth. 

Anticholinergics

Ipratropium Bromide

Nursing Care: #1 AIRWAY, Rescue inhaler (Albuterol), Oxygen, High fowler’s, rest to ↓ stress, & assess for signs and symptoms of hypoxia and respiratory failure.

Status Asthmaticus: Emergency, Oxygen, nebulizer medications, IV corticosteroids, & hydration.

  • Leukotriene Modifiers: Montelukast
  • Mast cell stabilizers: Cromolyn. Side effects: temporary burning sensation, teary eyes, sneezing, bad taste mouth. 
  • Omalizumab: Blocks immunoglobulin IgE. Given subQ in poorly controlled asthma

NCLEX Alerts

  • Always take bronchodilators first and 5 minutes after take the inhaled steroids.  The bronchodilator will open airways so steroids can enter airways and decrease inflammation.  E.g., Salmeterol first then Fluticasone.
  • For fastest relief of asthma symptoms the answer is albuterol (beta 2 agonist) or Ipratropium (anticholinergic).  Ipratropium is given to clients who cannot tolerate Albuterol. Alterol side effects are tachycardia and anxiety due to tachycardia. 
  • Use a spacer for steroid medications such as Fluticasone and budesonide to prevent thrush. Also gargle and rinse the mouth with water.  Spit the water.  Do not swallow. 

Asthma Types Based on Symptom Frequency

Asthma TypeFrequency of Symptoms
Mild Intermittent AsthmaSymptoms occur 2x/week or less
Mild Persistent AsthmaSymptoms occur more than 2x/week
Moderate Persistent AsthmaDaily symptoms with exacerbations 2x/week
Severe Persistent AsthmaConstant symptoms and frequent exacerbations

Action Plan

  • Asthma requires an action plan for when peak flow is below 50% normal. At this point, medication adjustments should be made by the PCP. Peak flow is a measure of how quickly clients can blow air out of their lungs. If they have asthma, they may have narrow airways. This will make it more difficult to blow the air out of their lungs quickly and can change their peak flow score.

The “personal or usual best” peak flow is the highest number a client can perform over a two-week period when asthma is under good control. Good control means the client feels good and does not have any symptoms.  The client then will compare all of other peak flow readings to his or her personal best peak flow number.

To find a personal best peak flow:

  • Perform peak flow testing twice a day for two weeks.
  • Do them at the same time in the morning and in the early evening.
  • Use this number to determine how well asthma is controlled and to identify a problem. 

Early Warnings of an asthma attack

  • Easily tired with activity
  • Reduced peak flow
  • Wheezing with activity
  • Nighttime coughing

Active asthma attack that requires intervention

  • Chest retractions
  • Cyanosis
  • No relief with albuterol

Metered Dose Inhaler

  • Steroid inhalers: rinse mouth and do not swallow water to prevent fungal infections/irritation/inflammation of the mouth. 
  • Administration of Metered Dose Inhaler (MDI)
  • Shake MDI before use for better delivery. Shake, shake, shake
  • Wait 1 minute between puffs for better absorption
  • Remember that wrapping the lips tightly around mouthpiece consolidates the medication in the buccal cavity and decreases effectiveness of inhaled medications. Lips should not be too tight
  • Use a 2 to 3 inch space or spacer device between the inhaler and the open mouth of the child to improve the effects of the medications.

Pulmonary Function Tests

  • A PFT consists of a clear, airtight box, soft nose clips, a mouthpiece and a small electronic machine that measures airflow (spirometer)
  • Before test hold bronchodilators and no smoking for at least 4 hours.
  • Avoid constricting clothes around chest
  • No heavy exercise before test

Theophylline

  • Theophylline (a xanthine medication) is used to prevent and treat wheezing, shortness of breath, and chest tightness caused by asthma, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, making it easier to breathe. Safe levels for people taking theophylline are often 8 to 20 mcg/mL.
  • Signs of toxicity: tachycardia, tachypnea, and hypotension.  NCLEX, if they are on theophylline always check levels to check toxicity. Macrolides such as erythromycin increases the chances of toxicity. Avoid Caffeine because Theophylline is from the same family as caffeine and the client will have stronger side effects. 

Respiratory Acidosis in asthma

  • Let’s look at symptoms of respiratory acidosis without compensation in asthma. Acute respiratory acidosis, right? Diaphoresis, headache, tachycardia, restlessness, confusion, apprehension, and flushed face.  Example of uncompensated respiratory acidosis ABG:  pH 7.30 PCO2 50 HCO3 25.  Note that the pH is abnormal so uncompensated. The client is retaining CO2 because the client cannot blow CO2 out due to airway swelling.

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