Genetic disorder that affects the lungs, pancreas, reproductive, digestive, skin and other organs. It is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. This gene normally provides instructions for making a protein that regulates the transport of salt and water in and out of cells. The CFTR protein is defective, leading to the production of thick, sticky mucus in the airways and other organs.
The thick mucus can obstruct the airways and make it difficult to breathe, leading to frequent lung infections, coughing, and wheezing. It can also cause problems with digestion and nutrient absorption in the intestines.
Cystic fibrosis is a chronic and progressive disease that requires lifelong management and treatment.
Cystic Fibrosis affects lungs, skin, pancreas, digestive, reproductive system and other organs