Hyperthyroidism vs. Hypothyroidism

Hyperthyroidism

↓ TSH & ↑ T3, T4

Hyperthyroidism

Causes

  • Graves Disease
  • Too much Iodine, ⇑ T3 and T4
  • Throid medication excess (Levothyroxine)

Labs

  • ⇓ TSH (thyroid-stimulating hormone)
  • ⇑ T3 & T4
  • Memorize it!
  • Pituitary produces TSH
  • If the pituitary sees that the thyroid is hyperactive (producing too much T3 & T4), it will slow down. Thus, TSH is low. 

Symptoms of Hyperthyroidism

When you think about signs and symptoms think fast and high.  High vital signs. Fast Metabolism. 

Vital Signs

↑ Temp

↑ BP

↑ Pulse

Palpitations

Heat Intolerance

Physical Signs

↑ Metabolism

Hot & sweaty

Exophthalmos

Irritable

Nervousness 

Insomnia

Tremors

GI Symptoms

↑ Appetite

Losing weight

Diarrhea

Eyes

Exophthalmos

Big protruding

Eyes

Patch eyes

to protect them

Treatment of Hyperthyroidism

Agranulocytosis and aplastic anemia are side effects of Methimazole and PTU.  PTU can be used in pregnancy. Avoid aspirin because it increases thyroid hormone. NCLEX Alert!

Methimazole

Cannot be used in first trimester. Use only in second trimester.  Take at the same time every day. Avoid foods high in iodine. Avoid aspirin because it increases thyroid hormone. Side effects: Agranulocytosis and aplastic anemia

PTU

Propylthiauracil: Only anti-thyroid medication that can be used in first trimester of pregnancy.  Take at the same time. Avoid food high in iodine. Avoid Aspirin.  Side effects: Agranulocytosis and aplastic anemia.

Beta Blockers

To decrease heart rate and blood pressure

Iodine Therapy

Side effects: taste changes and swollen salivary glands

Agranulocytosis is a serious condition where the body has a very low level of certain white blood cells called granulocytes. These cells are important for fighting off infections. When someone has agranulocytosis, their immune system is weakened, and they are at a higher risk of developing severe infections.

In aplastic anemia, all three types of blood cells—red blood cells, white blood cells, and platelets—are affected. The bone marrow fails to produce enough of these cells, leading to low levels in the bloodstream. Low platelets= bleeding.  Low WBC= infection. Low RBCs= fatigue and SOB.

Complications of Hyperthyroidism

  • Thyroid Storm/Thyrotoxic crisis
  • Severe symptoms of hyperthyroidism. It is a medical emergency
  • High temperature, tachycardia, systolic HTN, diarrhea, tremors, agitation, seizures, and coma.
  • Treatment: PTU, beta blockers, thyroidectomy.
  • NCLEX alert: Priority is to give beta blockers.  Think: What will work the fastest!  Anti-thyroid medications (PTU & Methimazole) take a while to work.
Thyroidectomy with life-long thyroid replacement

Thyroidectomy = Surgical Treatment

Thyroidectomy

Watch for thyroid storm after thyroidectomy because excessive T3 & T4 enters the bloodstream, causing severe hypertension, tachycardia, and elevated temperature

Hypocalcemia

Parathyroid is close to thyroid. It may have been damaged during surgery.

Laryngeal Nerve

Ask client to speak to check for laryngeal nerve damage after thyroidectomy

Respiratory Status

Swelling and hemorrhage can obstruct airway. Listen for stridor and have the tracheostomy tray at the bedside after thyroidectomy (PRIORITY)

Hypothyroidism

Slow and Low

Hypothyroidism

Causes

  • Hashimoto’s Disease
  • Low Iodine ⇓T3 and T4
  • Thyroidectomy
  • Pituitary Tumor
  • Anti-thyroid medication
  • Mostly Women

Labs

  • ⇑ TSH (thyroid-stimulating hormone)
  • ⇓ T3 & T4
  • The pituitary produces TSH, if it sees that the thyroid is hypoactive (producig low T3 & T 4), the pituitary gland will make more TSH

Symptoms of Hypothyroidism

Think low metabolism and low/slow when thinking about hypothyroidism

Vital Signs
  • Low HR, BP, RR, and Temp
Metabolism

Low appetite but gaining weight. Low metabolism.  Slow GI (Constipation)

Energy

Low mood/sex drive. Low mind/memory. Low interest/Apathy

Physical

Hair loss/Brittle nails. Puffy face. Myxedema (swelling). Intolerance to cold. Slow mentruation

Treatment

  • Levothyroxcine (hormone replacement)
  • Life-long treatment
  • Must take in the morning and in an empty stomach to increase absorption.
  • Do not give narcotics to these patients due to hypersensitivity
  • Maintain a warm environment

Complication of Hypothyroidism: Myxedema Coma

Myxedema = Swelling and extreme hypothyroidism symptoms

Is it Hypothyroidism or Hyperthyroidism?

Is it Hypothyroidism or Hyperthyroidism?

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