A malignant proliferation of plasma cells in the bone. Malignant plasma cells produce Bence Jones protein found in the blood and urine. Treatment is chemotherapy, radiation, steroids, and plasmapheresis (removal of immunoglobulins or abnormal antibodies)
Hypercalcemia, hyperuricemia, and proteinuria cause damage to kidneys
> 2L per day
To promote excretion of calcium
To protect kidneys & ↓ Calcium
Bones lose calcium (calcium moves into the serum. This is where hypercalcemia comes from). Bones become weaker.
to prevent falls. Encourage mobility
Such as pamidroate andzoledronic acid to slow down bone damamge and ↓ fractures
