TPN

Total Parenteral Nutrition

  • Dysfunctional GI tract
  • GI surgery
  • Intolerance to tube feedings
  • Malnutrition from burns, cancer, or chemotherapy
  • Least desirable form of nutrition. Only used when it is the only choice.

Indications

Administration

  • Administered via central line, peripherally inserted central catheter, or implanted vascular access
  • Hypertonic (high concentration of solutes and glucose > 15%

Composition

  • Glucose concentrations varies from 5% to 70%.
  • Amino acids
  • Lipids
  • Vitamins
  • Electrolytes
  • Insulin to counteract high glucose content.
Aseptic Techniquen when changing central line dressing and hanging new TPN. Monitor signs and symptoms of infection.

Nursing Interventions

  • Never stop TPN abruptly, wean down. 
  • Once discontinued check blood sugar 1 hour after. 
  • Weight patient daily
  • Never increase rate for “catch up”
  • Monitor I & O
  • Aseptic Technique when changing TPN
  • Hang D10W if you run out of TPN
  • Monitor glucose every 4 hours with insulin sliding scale
  • Monitor Electrolytes
  • Return cloudy/dark solution 
  • Must be hung within 24 hours of preparation by pharmacy

Complications

Fluid overload: hypertension, edema, dyspnea, crackles. Elevate HOB. Reduce rate per MD order
Pneumothorax from incorrect catheter placement. Make sure an x-ray is done for correct placement.
Infection: Monitor for fever, chills, nausea, vomiting, redness and swelling at insertion site
Air embolism: Air enters vein through tubing. Clamp tubing and turn patient left trendelenburg position

Peripheral Parenteral Nutrition

  • Given through a peripheral IV
  • Low glucose concentration  (< 12.5% glycose)
  • Used for short term (5 to 7 days) 
  • Used when client needs smaller concentration of carbs, fats, and proteins
  • PPN delivers isotonic or midly hypertonic solutions since highly hypertonic solutions can cause sclerosis, phlebitis, or swelling to peripheral veins.
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