Aplastic Anemia
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Aplastic Anemia
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Patho
- ⇓ Red blood cells due to bone marrow suppression.
- can occur alone or with leukopenia (⇓ WBcs) or thrombocytopenia (⇓ Platelets).
- Occurs in oncology and it is diagnosed by bone marrow aspiration and biopsy.
- Cytotoxic drugs
- Exposure to toxic chemicals
- Radiation
- Autoimmine disorders
- Viral infections
- Bone marrow suppression causes ⇓ RBCs, ⇓ WBCs, & ⇓ platelets)
- Macrocytic anemia⇒ red blood cells are large.
- Anemia symptoms: weakness, fatigue, pallor, shortness of breathe, dizziness
- ⇓ WBCs = risk for infection
- Low platelets⇒ easy bleeding: petechiae (small pots on the skin, mouth and lips).
- Ecchymosis: bruising
- Stem cell transplant
- Blood transfusion as needed
- Prednisone or cyclosporine